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Cholecystectomy and post-operative complications from over 9000 surgical cases

Dataset
Version: 1.0.0
A deeply phenotyped dataset of hospitalised patients undergoing an emergency or elective cholecystectomy. Longitudinal granular demographics, co-morbidities, laboratory results, physiology, medications, complications including sepsis and outcomes.

Summary

Citation:
Cholecystectomy and post-operative complications from over 9000 surgical cases

Documentation

Description:
Cholecystectomy is a common surgical procedure to remove the gall bladder, with over 1.2 million procedures performed in the USA each year. The most common indication is recurrent gall stones. The main operative incidents are haemorrhage, iatrogenic perforation of the gallbladder, and common bile duct (CBD) injuries. The main post-operative complications are sepsis, sub-hepatic abscess, haemorrhage, bile leakage and retained bile duct stones, with sepsis the most common post-operative complications. Sepsis post-surgery is costly to the individual, associated with a reduced quality of life, increased length of stay, pain, loss of function and mortality. Although risk factors for developing sepsis are recognised, these cannot be applied at an individual level, making it difficult to predict who might develop sepsis, in order to implement mitigation strategies. This dataset includes 9,400 individual surgical cases for cholecystectomy, including both elective and emergency surgery. The data includes detailed patient demography, measures of socio-economic deprivation, co-morbidities, the surgical indication, all physiological and pathological measurements, the surgery performed, anaesthetic used, medications given, complications and outcomes. PIONEER geography: The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. Electronic Health Record: UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & an expanded 250 ITU bed capacity during COVID. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”. Scope: Patients that had an emergency or elective Cholecystectomy procedure during their hospital stay. Longitudinal & individually linked, so that the preceding & subsequent health journey can be mapped & healthcare utilisation prior to & after admission understood. The dataset includes highly granular patient demographics, co-morbidities taken from ICD-10 & SNOMED-CT codes. Serial, structured data pertaining to process of care (timings, admissions, wards), presenting complaint, physiology readings (e.g. heart rate, blood pressure, respiratory rate, NEWS2 score and oxygen saturations), Lab analysis results (Alanine Transferase, albumin, EGFR, Creatine Kinase, White Blood Cells and others), microbiology results, surgery, medications, complications and all outcomes. Available supplementary data: Matched controls; ambulance, OMOP data, synthetic data. Available supplementary support: Analytics, Model build, validation & refinement; A.I.; Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.
Is Part Of:
NOT APPLICABLE

Coverage

Spatial:
United Kingdom, England, West Midlands
Typical Age Range:
18-93
Follow Up:
OTHER
Physical Sample Availability:
NOT AVAILABLE
Pathway:
Data is representative of the multi-ethnicity population within the West Midlands (42% non white). Data includes all patients admitted during this timeframe, with National data Opt Outs applied, and therefore is representative of admissions to secondary care. Data focuses on in-patient stay in hospital during the acute episode but can be supplemented on request to include previous and subsequent hospital contacts (including outpatient appointments) and ambulance, 111, 999 data.

Provenance

Origin

Purposes:
CARE
Sources:
EPR
Collection Situations:
  • ACCIDENT AND EMERGENCY
  • IN-PATIENTS

Temporal

Accrual Periodicity:
QUARTERLY
Distribution Release Date:
2021-12-06
Start Date:
2004-02-25
End Date:
2021-07-30
Time Lag:
OTHER

Accessibility

Access

Access Service:
Trusted Research Environments (TRE) are built using Microsoft Azure services and hosted in the UK to provide research teams a safe, secure and agile environment which allows users to quickly analyse, interpret and form an enriched view of primary care information through a range of integrated datasets. Health data collated from multiple sources is ingested into a secure data lake which will then allow subsets of data to be made available to research teams on approval of a data request. Once approved a customer specific TRE is made available with a standard set of leading analytical tools from Microsoft including Azure Databricks, Azure Machine Learning, Azure SQL and Azure Synapse (for large-scale data warehouses). Specific tools can be provided at an additional cost over the standard platform data access charge and the PIONEER team will work with you to determine your exact needs. Access to the TRE is managed using the latest virtual desktop technology to provide a safe and secure end-user experience. By utilising leading edge design PIONEER are able to create TREs rapidly to enable us to service any customer requirement.
Access Request Cost:
www.pioneerdatahub.co.uk/data/data-services-costs/
Delivery Lead Time:
1-2 MONTHS
Jurisdictions:
GB-ENG
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
NOT APPLICABLE

Usage

Data Use Limitations:
GENERAL RESEARCH USE
Data Use Requirements:
PROJECT SPECIFIC RESTRICTIONS
Resource Creators:
  • This publication uses data from PIONEER
  • an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)

Format and Standards

Vocabulary Encoding Schemes:
  • ICD10
  • OPCS4
  • SNOMED CT
Conforms To:
LOCAL
Languages:
en
Formats:
SQL

Enrichment and Linkage

Derivations:
Not Available

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Events
9,485 elective and emergency admissions with Cholecystectomy procedures
9485
Count
2021-12-06