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The impact of COVID on hospitalised patients with COPD; a dataset in OMOP

Dataset
Version: 1.0.0
Hospital patients admitted during the COVID pandemic with a focus on COPD. Granular condition, multi-morbidity. Serial physiology, blood biomarkers, treatments, interventions, ITU spells, outcome, pre/post admission healthcare use. Deeply phenotyped.

Summary

Citation:
The impact of COVID on hospitalised patients with COPD; a dataset in OMOP

Documentation

Description:
Background. Chronic obstructive pulmonary disease (COPD) is a debilitating lung condition characterised by progressive lung function limitation. COPD is an umbrella term and encompasses a spectrum of pathophysiologies including chronic bronchitis, small airways disease and emphysema. COPD caused an estimated 3 million deaths worldwide in 2016, and is estimated to be the third leading cause of death worldwide. The British Lung Foundation (BLF) estimates that the disease costs the NHS around £1.9 billion per year. COPD is therefore a significant public health challenge. This dataset explores the impact of hospitalisation in patients with COPD during the COVID pandemic. PIONEER geography The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. There is a higher than average percentage of minority ethnic groups. WM has a large number of elderly residents but is the youngest population in the UK. There are particularly high rates of physical inactivity, obesity, smoking & diabetes. The West Midlands has a high prevalence of COPD, reflecting the high rates of smoking and industrial exposure. Each day >100,000 people are treated in hospital, see their GP or are cared for by the NHS. EHR. University Hospitals Birmingham NHS Foundation Trust (UHB) is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & 100 ITU beds. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”. Scope: All hospitalised patients admitted to UHB during the COVID-19 pandemic first wave, curated to focus on COPD. Longitudinal & individually linked, so that the preceding & subsequent health journey can be mapped & healthcare utilisation prior to & after admission understood. The dataset includes ICD-10 & SNOMED-CT codes pertaining to COPD and COPD exacerbations, as well as all co-morbid conditions. Serial, structured data pertaining to process of care (timings, staff grades, specialty review, wards), presenting complaint, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations), all blood results, microbiology, all prescribed & administered treatments (fluids, nebulisers, antibiotics, inotropes, vasopressors, organ support), all outcomes. Linked images available (radiographs, CT). Available supplementary data: More extensive data including wave 2 patients in non-OMOP form. Ambulance, 111, 999 data, synthetic data. Available supplementary support: Analytics, Model build, validation & refinement; A.I.; Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.
Is Part Of:
NOT APPLICABLE

Coverage

Spatial:
United Kingdom, England, West Midlands
Typical Age Range:
18-108
Follow Up:
0 - 6 MONTHS
Physical Sample Availability:
NOT AVAILABLE
Pathway:
Data focuses on in-patient stay in hospital during the acute episode but can be supplemented on request to include previous and subsequent hospital contacts (including outpatient appointments) and ambulance, 111, 999 data. Data includes those with and without COPD admitted during the first wave of the COVID pandemic.

Provenance

Origin

Purposes:
OTHER
Sources:
EPR
Collection Situations:
  • COMMUNITY
  • IN-PATIENTS
  • OUTPATIENTS

Temporal

Accrual Periodicity:
STATIC
Distribution Release Date:
2020-12-08
Start Date:
2020-01-01
End Date:
2020-09-09
Time Lag:
LESS 1 WEEK

Accessibility

Access

Access Service:
Trusted Research Environment on Microsoft Azure cloud server (UK South). Creating the environment will be subject to a charge following approval of data request. The PIONEER team will work with you to ensure the relevant compute power and tooling is available to support your analytical needs.
Delivery Lead Time:
1-2 MONTHS
Jurisdictions:
GB
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
Not Applicable

Usage

Data Use Limitations:
RESEARCH USE ONLY
Data Use Requirements:
COLLABORATION REQUIRED
Resource Creators:
  • This publication uses data from PIONEER
  • an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)

Format and Standards

Vocabulary Encoding Schemes:
  • ICD10
  • SNOMED CT
Conforms To:
OMOP
Languages:
en
Formats:
SQL

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Events
50,887 patients including COPD and non-COPD control group
50,887
COUNT
2020-12-08