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Ventilatory strategies and outcomes for patients with COVID: a dataset in OMOP

Dataset
Version: 1.0.0
Hospital patients admitted during the COVID pandemic requiring/at risk of requiring ventilatory support. Granular condition, multi-morbidity, interventions and treatments. Serial physiology, blood biomarkers, ITU spells, outcome. Deeply phenotyped.

Summary

Citation:
Ventilatory strategies and outcomes for patients with COVID: a dataset in OMOP

Documentation

Description:
Background. Coronavirus disease 2019 (COVID-19) was identified in January 2020. Currently, there have been more than 6 million cases & more than 1.5 million deaths worldwide. Some individuals experience severe manifestations of infection, including viral pneumonitis, adult respiratory distress syndrome (ARDS) & death. Many patients required ventilatory support including high flow oxygen, continuous positive airway pressure and intubated with or without tracheotomy. Different centres took different approaches to care delivery depending on ITU bed availability. This secondary care COVID OMOP dataset contains granular ventilatory, demographic, morbidity, serial acuity and outcome data in COVID-19. PIONEER geography The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. There is a higher than average percentage of minority ethnic groups. WM has a large number of elderly residents but is the youngest population in the UK. Each day >100,000 people are treated in hospital, see their GP or are cared for by the NHS. The West Midlands was one of the hardest hit regions for COVID admissions in both wave 1 & 2. EHR. University Hospitals Birmingham NHS Foundation Trust (UHB) is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & 100 ITU beds. ITU capacity increased to 250 beds during the COVID pandemic. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”. UHB has cared for >5000 COVID admissions to date. This data is in the OMOP format. Scope: All COVID swab confirmed hospitalised patients to UHB from January – September 2020. The dataset includes highly granular patient demographics & co-morbidities taken from ICD-10 & SNOMED-CT codes. Serial, structured data pertaining to care process (timings, staff grades, specialty review, wards), severity, ventilatory requirements, acuity, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations), all blood results, microbiology, all prescribed & administered treatments (fluids, antibiotics, inotropes, vasopressors, organ support), all outcomes. Available supplementary data: More extensive data including wave 2 patients in non-OMOP form. Ambulance, 111, 999 data, synthetic data. Available supplementary support: Analytics, Model build, validation & refinement; A.I.; Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.

Coverage

Spatial:
United Kingdom, England, West Midlands
Typical Age Range:
18-108
Follow Up:
0 - 6 MONTHS
Physical Sample Availability:
NOT AVAILABLE
Pathway:
Data focuses on in-patient stay in hospital during the acute episode but can be supplemented on request to include previous and subsequent hospital contacts (including outpatient appointments) and ambulance, 111, 999 data. Data includes those with and without COVID admitted during the first wave of the COVID pandemic.

Provenance

Origin

Purposes:
OTHER
Sources:
EPR
Collection Situations:
  • COMMUNITY
  • IN-PATIENTS
  • OUTPATIENTS

Temporal

Accrual Periodicity:
STATIC
Distribution Release Date:
2020-12-08
Start Date:
2020-01-01
End Date:
2020-09-09
Time Lag:
LESS 1 WEEK

Accessibility

Access

Access Service:
Trusted Research Environment on Microsoft Azure cloud server (UK South). Creating the environment will be subject to a charge following approval of data request. The PIONEER team will work with you to ensure the relevant compute power and tooling is available to support your analytical needs.
Delivery Lead Time:
1-2 WEEKS
Jurisdictions:
GB
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Data Processor:
NOT APPLICABLE

Usage

Data Use Limitations:
RESEARCH USE ONLY
Resource Creators:
  • This publication uses data from PIONEER
  • an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)

Format and Standards

Vocabulary Encoding Schemes:
  • ICD10
  • SNOMED CT
Conforms To:
OMOP
Languages:
en
Formats:
SQL

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Events
50902 patients including those on ventilation and an unventilated control group
50902
EVENTS
2020-12-08